贝伐单抗治疗神经纤维瘤病II型

AnticancerDrugRestoresHearinginSomePatientswithNeurofibromatosis

Inasmallclinicalstudywithananticancerdrugthathaltsbloodvesselgrowth,ahandfulofpeoplewithneurofibromatosistype2(NF2)andhearinglosshadrestorationofhearing.ResultsofthecollaborativestudybyresearchersatJohnsHopkinsMedicine,theNationalInstitutesofHealthandMassachusettsGeneralHospitalweredescribedonlineMarch14intheJournalofClinicalOncology.

Anestimatedonein25,peopleisbornwithNF2,ahereditarytumorsyndromeinwhichvirtuallyeveryoneprogressestodeafnessbecauseofvestibularschwannomas—tumorsgrowingonthenervesresponsibleforhearing.ThetumorsarisefromtheSchwanncellsthatsupportandinsulatenerves.Thesetumorsalsocausebalanceproblemsandbrainstem







































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